BDBM534131 WO2022081842, Example 7

SMILES Cc1ccc(c(c1)-c1ccccc1)S(=O)(=O)NC(=O)c1cc2c(C)cc(C)cc2o1

InChI Key InChIKey=JFFDRYBVVLPPHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534131   

TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534131(WO2022081842, Example 7)
Affinity DataIC50:  114nMAssay Description: Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM534131(WO2022081842, Example 7)
Affinity DataIC50:  87nMAssay Description: Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed