BDBM534243 ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl ((S)-2-((3-cyano-5-fluorobenzyl)oxy)-3-(octadecylamino)-3-oxopropyl) hydrogen phosphate (47)::WO2022081973, Example 47

SMILES CCCCCCCCCCCCCCCCCCNC(=O)[C@H](COP(O)(=O)OC[C@H]1O[C@](C#N)([C@H](O)[C@@H]1O)c1ccc2c(N)ncnn12)OCc1cc(F)cc(c1)C#N

InChI Key InChIKey=RYENBAIIJQHROI-GZYRZLQQSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 534243   

TargetFusion glycoprotein F0(Human respiratory syncytial virus A (strain A2))
Gilead Sciences

WIPO
LigandPNGBDBM534243(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataEC50:  32nMAssay Description:Antiviral activity of compounds against SARS-CoV-2 is evaluated as described in Xue, Xi et al.2020. Briefly, the human alveolar epithelial cell line ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gilead Sciences

WIPO
LigandPNGBDBM534243(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataEC50:  120nMAssay Description:Antiviral activity of compounds against SARS-CoV-2 is evaluated as described in Xue, Xi et al.2020. Briefly, the human alveolar epithelial cell line ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed