BDBM535275 WO2022021841, 28
SMILES COc1ccc(OCC(=O)N2C[C@H]3[C@@H](C2C(=O)N[C@@H](C[C@@H]2CCNC2=O)C=O)C3(C)C)cc1F
InChI Key InChIKey=ITLIZQKXLAJTCO-JJDIHXCJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 535275
Affinity DataKi: 47nMAssay Description:SARS-CoV-2 Mpro (final concentration 750 nM) plus every compound in 25 uL of buffer (20 mM Tris-HCl, pH 7.5, 150mM NaCl,1mM EDTA,2mM DT...More data for this Ligand-Target Pair
Affinity DataEC50: 4.68E+3nMAssay Description:Vero E6 cells were plated at 20,000 cells/well in a 96-well plate. 24hr later, medium containing a dose response of NHC was added concurrent with SAR...More data for this Ligand-Target Pair