BDBM54549 1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)-1-propanone::1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-1-one::1-[4-(2,5-dimethylphenyl)piperazino]-3-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-1-one::KUC103356N::UNM-0000306070::cid_25241706

SMILES Cc1ccc(C)c(c1)N1CCN(CC1)C(=O)CCc1nc(no1)-c1ccccc1

InChI Key InChIKey=KOKQBQSCGZSNAT-UHFFFAOYSA-N

Data  7 KI  8 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 54549   

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  80nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  100nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  140nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  150nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  250nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataKi:  850nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  4.00E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-2A(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  841nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related protein Rab-7a(Canis lupus familiaris)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  1.16E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  1.64E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetGTPase KRas [1-37](Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  869nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetCell division control protein 42 homolog(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  621nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetRas-related C3 botulinum toxin substrate 1(Mus musculus)
Nmmlsc

Curated by PubChem BioAssay

LigandBDBM54549(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-(3-phen...)Copy SMILESCopy InChI

Affinity DataEC50:  2.79E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails PCBioAssay
Copy BDB DOI