BDBM547920 WO2022090481, Example I-141

SMILES CCc1nc(cc2n(C)c(=O)n(C)c12)-n1ncc2c(C)nc(cc12)-c1cnccc1OC

InChI Key InChIKey=OLDQXYDWRORFSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547920   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Homo sapiens (Human))
Boehringer Ingelheim International

WIPO
LigandPNGBDBM547920(WO2022090481, Example I-141)
Affinity DataIC50:  1.60nMAssay Description: Ba/F3 cells were ordered from DSMZ (ACC300, Lot17) and grown in RPMI-1640 (ATCC 30-2001) + 10 % FCS + 10 ng/ml IL-3 at 37 °C in 5 % CO2 atmosphere. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed