BDBM548267 (R)-7'-isopropyl-2'-((R)-3-methylmorpholino)-7'H-spiro[cyclopropane-1,6'-pyrazolo[1,5-a]pyrazin]-4'(5'H)-one::WO2022093820, Compound 33

SMILES CC(C)[C@H]1n2nc(cc2C(=O)NC11CC1)N1CCOC[C@H]1C

InChI Key InChIKey=BOUSJPKIEBGQER-BXUZGUMPSA-N

Data  1 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548267   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
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WIPO
LigandPNGBDBM548267((R)-7'-isopropyl-2'-((R)-3-methylmorpholino)-7'H-s...)
Show SMILES CC(C)[C@H]1n2nc(cc2C(=O)NC11CC1)N1CCOC[C@H]1C
Show InChI InChI=1S/C16H24N4O2/c1-10(2)14-16(4-5-16)17-15(21)12-8-13(18-20(12)14)19-6-7-22-9-11(19)3/h8,10-11,14H,4-7,9H2,1-3H3,(H,17,21)/t11-,14-/m1/s1
Affinity DataIC50: 24nMAssay Description: [0194] Experimental compound in DMSO was dispensed to a 384-well microplate via acoustic dispenser at 50 nl per well. At 2.5 Ál per well, an enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed