BDBM548301 WO2022093820, Compound 69

SMILES C[C@@H](CO)C1CNC(=O)c2cc(nn12)N1CCOC[C@H]1C

InChI Key InChIKey=XMNNRXPKUYJRRT-YPBKCWQDSA-N

Data  1 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548301   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
GENENTECH, INC.

WIPO
LigandPNGBDBM548301(WO2022093820, Compound 69)
Show SMILES C[C@@H](CO)C1CNC(=O)c2cc(nn12)N1CCOC[C@H]1C
Show InChI InChI=1S/C14H22N4O3/c1-9(7-19)12-6-15-14(20)11-5-13(16-18(11)12)17-3-4-21-8-10(17)2/h5,9-10,12,19H,3-4,6-8H2,1-2H3,(H,15,20)/t9-,10+,12?/m0/s1
Affinity DataIC50: 784nMAssay Description: [0194] Experimental compound in DMSO was dispensed to a 384-well microplate via acoustic dispenser at 50 nl per well. At 2.5 Ál per well, an enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed