BDBM548846 WO2022098806, Compound 2-107::WO2022098806, Compound 2-184::WO2022098806, Compound 2-185
SMILES CN1CCc2cc(F)c(Nc3ncc4c(N)c(F)c(c(Cl)c4n3)-c3cnc4OCCNc4c3C)cc2C1
InChI Key InChIKey=AKFOSIZLCQSOSQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 548846
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp
WIPO
Merck Sharp &Amp
WIPO
Affinity DataIC50: 0.0900nMAssay Description: To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp
WIPO
Merck Sharp &Amp
WIPO
Affinity DataIC50: 0.0300nMAssay Description: To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp
WIPO
Merck Sharp &Amp
WIPO
Affinity DataIC50: 3.67nMAssay Description: To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &...More data for this Ligand-Target Pair