BDBM548884 WO2022098806, Compound 2-145

SMILES CC(C)N1CCc2ccc(Nc3ncc4c(N)c(F)c(cc4n3)-c3cnc4OC(C)CNc4c3C)cc2C1

InChI Key InChIKey=RKTMKSARXKXGFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548884   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM548884(WO2022098806, Compound 2-145)
Affinity DataIC50:  0.0500nMAssay Description: To each well of black Corning #3820384-well plate, an ECHO was used to dispense 7.5 nL of DMSO or Test compound in DMSO. A 1.5x kinase solution, 5 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed