BDBM6219 BMCL182776 Compound 1::Chlorobenzodioxole deriv. 28::N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-amine
SMILES COc1cc2c(Nc3c4OCOc4ccc3Cl)ncnc2cc1OCCCN1CCCCC1
InChI Key InChIKey=QHIMVPIOWKYPSO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 6219
Affinity DataIC50: 2.17E+4nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit receptor tyrosine kinase activity. The compounds were incubated with enzym...More data for this Ligand-Target Pair
Affinity DataIC50: <4nMT: 2°CAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit receptor tyrosine kinase activity. The compounds were incubated with enzym...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as reduction in BrdU incorporation after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of human recombinant pp60c-src expressed in baculovirus infected Sf9 insect cells using poly(Glu,Tyr) 4:1 as substrate after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit receptor tyrosine kinase activity. The compounds were incubated with enzym...More data for this Ligand-Target Pair