BDBM6436 3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-thiazol-2-yl)amino]propan-1-ol::3-{[5-[6-((3-Chlorophenyl)amino)pyrazin-2-yl]thiazol-2-yl]amino}propan-1-ol::pyrazine-thiazol deriv.59

SMILES OCCCNc1ncc(s1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=UJWGPYCAVBVVHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6436   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6436(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-...)
Affinity DataIC50:  708nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6436(3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-...)
Affinity DataIC50:  8.08E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed