BDBM6437 (3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxazol-5-yl]pyrazin-2-yl}carbamic Acid tert-Butyl Ester::3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-oxazol-2-yl)amino]propan-1-ol::pyrazine-oxazol deriv.62

SMILES OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=YMNUEHRMMXCIPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6437   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6437((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...)
Affinity DataIC50:  2.11E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6437((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...)
Affinity DataIC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed