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BDBM70698 US9693997, 217

SMILES: CC(C)(C)NS(=O)(=O)c1ccc(cc1OC(F)(F)F)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F

InChI Key: InChIKey=XTAAFFLURUTZCB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70698   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA polymerase (NS5B)


(Hepatitis C virus (HCV))
BDBM70698
PNG
(US9693997, 217)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(cc1OC(F)(F)F)-c1c(Cl)cc(Nc2n[nH]c(N)n2)cc1C(F)(F)F
Show InChI InChI=1S/C20H19ClF6N6O3S/c1-18(2,3)33-37(34,35)14-5-4-9(6-13(14)36-20(25,26)27)15-11(19(22,23)24)7-10(8-12(15)21)29-17-30-16(28)31-32-17/h4-8,33H,1-3H3,(H4,28,29,30,31,32)
PDB

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/an/an/a 3n/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Plasmids expressing HCV E1 and E2 envelope proteins of GT1a H77 strain (Proc Natl Acad Sci USA 1997 94:8738-43) or GT1b Con1 strain (Science 1999 285...


US Patent US9693997 (2017)


BindingDB Entry DOI: 10.7270/Q2833Q56
More data for this
Ligand-Target Pair