BDBM7126 3-Propylaminopyrazole deriv. 3::CHEMBL112442::CS2::N-(5-Cyclopropyl-1H-pyrazol-3-yl)butanamide
SMILES CCCC(=O)Nc1cc([nH]n1)C1CC1
InChI Key InChIKey=KPQLRNNPRYBTLP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 7126
Affinity DataIC50: 224nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataKd: 1.84E+3nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
Affinity DataKd: 3.97E+3nMpH: 7.5 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKoff: 4.68E+6s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Affinity DataKoff: 2.22E+5s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Affinity DataKon: 0.381M-1s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 2 hits for monomerid = 7126
ITC DataΔG°: -8.55kcal/mole −TΔS°: 1.64kcal/mole ΔH°: -10.2kcal/mole logk: 1.89E+6
T: 24.85°C
T: 24.85°C
ITC DataΔG°: -7.33kcal/mole −TΔS°: 1.43kcal/mole ΔH°: -8.77kcal/mole logk: 2.41E+5
T: 24.85°C
T: 24.85°C