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BDBM71502 US9694002, 524

SMILES: Fc1cc(CN2CCC(CC2)Oc2ncc(cc2Cl)C(F)(F)F)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1

InChI Key: InChIKey=LMRLMSNXUMMQMU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 71502   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium Channel Complex


(Homo sapiens (Human))
BDBM71502
PNG
(US9694002, 524)
Show SMILES Fc1cc(CN2CCC(CC2)Oc2ncc(cc2Cl)C(F)(F)F)c(cc1C(=O)NS(=O)(=O)C1CC1)C1CC1
Show InChI InChI=1S/C25H26ClF4N3O4S/c26-21-10-16(25(28,29)30)12-31-24(21)37-17-5-7-33(8-6-17)13-15-9-22(27)20(11-19(15)14-1-2-14)23(34)32-38(35,36)18-3-4-18/h9-12,14,17-18H,1-8,13H2,(H,32,34)
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Similars

US Patent
n/an/a 11n/an/an/an/a7.425



Genentech Inc

US Patent


Assay Description
Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...


US Patent US9694002 (2017)


BindingDB Entry DOI: 10.7270/Q24B2ZFG
More data for this
Ligand-Target Pair