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BDBM71549 VU0410190-1::[2-(2-furanyl)-4-quinolinyl]-(4-phenyl-1-piperidinyl)methanone::[2-(2-furyl)-4-quinolyl]-(4-phenylpiperidino)methanone::[2-(furan-2-yl)quinolin-4-yl]-(4-phenylpiperidin-1-yl)methanone::cid_39582163

SMILES: O=C(N1CCC(CC1)c1ccccc1)c1cc(nc2ccccc12)-c1ccco1

InChI Key: InChIKey=RGCGDQMGVOXMKH-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 71549   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
neuronal munc18-1 binding protein


(Rattus norvegicus)
BDBM71549
PNG
(VU0410190-1 | [2-(2-furanyl)-4-quinolinyl]-(4-phen...)
Show SMILES O=C(N1CCC(CC1)c1ccccc1)c1cc(nc2ccccc12)-c1ccco1
Show InChI InChI=1S/C25H22N2O2/c28-25(27-14-12-19(13-15-27)18-7-2-1-3-8-18)21-17-23(24-11-6-16-29-24)26-22-10-5-4-9-20(21)22/h1-11,16-17,19H,12-15H2
PDB
MMDB

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Similars

Article
PCBioAssay
n/an/a>5.68E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


Article DOI: 10.1016/j.bioorg.2014.07.011
BindingDB Entry DOI: 10.7270/Q2668BMS
More data for this
Ligand-Target Pair