BDBM71742 7-amino-4-methyl-1-benzopyran-2-one::7-amino-4-methyl-coumarin::7-amino-4-methylchromen-2-one::7-azanyl-4-methyl-chromen-2-one::EN300-05587::MLS000057660::SMR000067752::cid_92249

SMILES Cc1cc(=O)oc2cc(N)ccc12

InChI Key InChIKey=GLNDAGDHSLMOKX-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

PDB links: 21 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 71742   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataKi:  5.56E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataKi:  7.64E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataKi:  9.13E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 after 6 hrs by stop-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM71742(7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...)
Affinity DataIC50:  1.70E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed