BDBM724 (3S)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-5-{[(2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}-1-phenylpentan-2-yl]carbamate::Pyrrolinone deriv. 5::Pyrrolinone inhibitor 5

SMILES [H][C@](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)(Cc1ccccc1)C(=O)NC1[C@H](O)Cc2ccccc12

InChI Key InChIKey=PKJPLBXKJRGYRL-ZNTXGADESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 724   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
University Of Pennsylvania

LigandPNGBDBM724((3S)-oxolan-3-yl N-[(2S,3S,5R)-5-benzyl-3-hydroxy-...)
Affinity DataIC50:  0.0300nMpH: 5.5 T: 2°CAssay Description:All enzyme assays were performed under initial velocity and steady-state conditions. The conditions for the enzyme catalyzed hydrolysis of the cleava...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed