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BDBM72718 1-Methyl-1H-indole-3-carboxylic acid [1-(4-bromo-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::MLS000333260::N-[(4-bromanylthiophen-2-yl)methylideneamino]-1-methyl-indole-3-carboxamide::N-[(4-bromo-2-thienyl)methyleneamino]-1-methyl-indole-3-carboxamide::N-[(4-bromo-2-thiophenyl)methylideneamino]-1-methyl-3-indolecarboxamide::N-[(4-bromothiophen-2-yl)methylideneamino]-1-methylindole-3-carboxamide::SMR000436549::cid_2048117

SMILES: Cn1cc(C(=O)NN=Cc2cc(Br)cs2)c2ccccc12

InChI Key: InChIKey=BDQNAKXWAJQBRR-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72718   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hsf1 protein


(Mus musculus)
BDBM72718
PNG
(1-Methyl-1H-indole-3-carboxylic acid [1-(4-bromo-t...)
Show SMILES Cn1cc(C(=O)NN=Cc2cc(Br)cs2)c2ccccc12
Show InChI InChI=1S/C15H12BrN3OS/c1-19-8-13(12-4-2-3-5-14(12)19)15(20)18-17-7-11-6-10(16)9-21-11/h2-9H,1H3,(H,18,20)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a 4.29E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2P55KXK
More data for this
Ligand-Target Pair