BDBM7417 (2 Z,3 E)-6-Fluoroindirubin-3 -acetoxime::6-fluoroindirubin-3 -acetoxime::[(3E)-2-[(3Z)-6-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-dihydro-1H-indol-3-ylidene]amino acetate::indirubin deriv. 8b

SMILES CC(=O)ON=C1C(Nc2ccccc12)=C1C(=O)Nc2cc(F)ccc12

InChI Key InChIKey=BARYIBSYXHNCQE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7417   

TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
University Of Athens

LigandPNGBDBM7417((2 Z,3 E)-6-Fluoroindirubin-3 -acetoxime | 6-fluor...)
Affinity DataIC50:  300nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Athens

LigandPNGBDBM7417((2 Z,3 E)-6-Fluoroindirubin-3 -acetoxime | 6-fluor...)
Affinity DataIC50:  600nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Porcine)
University Of Athens

LigandPNGBDBM7417((2 Z,3 E)-6-Fluoroindirubin-3 -acetoxime | 6-fluor...)
Affinity DataIC50:  90nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed