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BDBM74938 2-[(5Z)-4-keto-5-p-anisylidene-2-thioxo-thiazolidin-3-yl]acetic acid [2-(2-chloro-4-methyl-anilino)-2-keto-ethyl] ester::2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]acetic acid [2-(2-chloro-4-methylanilino)-2-oxoethyl] ester::MLS000375204::SMR000254457::[2-(2-chloro-4-methylanilino)-2-oxoethyl] 2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetate::[2-[(2-chloranyl-4-methyl-phenyl)amino]-2-oxidanylidene-ethyl] 2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanoate::cid_2381082

SMILES: COc1ccc(\C=C2/SC(=S)N(CC(=O)OCC(=O)Nc3ccc(C)cc3Cl)C2=O)cc1

InChI Key: InChIKey=CIIKRGRNZARRHF-ZDLGFXPLSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 74938   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM74938
PNG
(2-[(5Z)-4-keto-5-p-anisylidene-2-thioxo-thiazolidi...)
Show SMILES COc1ccc(\C=C2/SC(=S)N(CC(=O)OCC(=O)Nc3ccc(C)cc3Cl)C2=O)cc1
Show InChI InChI=1S/C22H19ClN2O5S2/c1-13-3-8-17(16(23)9-13)24-19(26)12-30-20(27)11-25-21(28)18(32-22(25)31)10-14-4-6-15(29-2)7-5-14/h3-10H,11-12H2,1-2H3,(H,24,26)/b18-10-
PDB
MMDB

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PC sid
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Similars

Article
PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


Article DOI: null
BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair