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BDBM75121 5-(2,4-dimethylphenyl)-7-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine::MLS000541712::SMR000472249::cid_16738672

SMILES: Cc1ccc(C2=Nc3ncnn3C(C2)c2ccccc2)c(C)c1

InChI Key: InChIKey=TWUSYIDVFIAXJN-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens (Human))
BDBM75121
PNG
(5-(2,4-dimethylphenyl)-7-phenyl-1,7-dihydro-[1,2,4...)
Show SMILES Cc1ccc(C2=Nc3ncnn3C(C2)c2ccccc2)c(C)c1
Show InChI InChI=1S/C19H18N4/c1-13-8-9-16(14(2)10-13)17-11-18(15-6-4-3-5-7-15)23-19(22-17)20-12-21-23/h3-10,12,18H,11H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

PCBioAssay
n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair