BDBM761 Hydroxyethylene deriv. 12::tert-butyl N-[(2S,3S,5R)-5-({1-[(1H-1,3-benzodiazol-2-ylmethyl)carbamoyl]-2-methylbutyl}carbamoyl)-5-benzyl-3-hydroxy-1-phenylpentan-2-yl]carbamate

SMILES CCC(C)C(NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc1ccccc1)C(=O)NCc1nc2ccccc2[nH]1

InChI Key InChIKey=BINCYFHKHSPQAO-AUDVFALKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 761   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM761(Hydroxyethylene deriv. 12 | tert-butyl N-[(2S,3S,5...)
Affinity DataIC50:  0.0700nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed