BDBM76289 MLS001249435::SMR000718656::[2-[(4-chlorophenyl)carbamoyl]-4,6-bis(iodanyl)phenyl] ethanoate::[2-[(4-chlorophenyl)carbamoyl]-4,6-diiodophenyl] acetate::acetic acid [2-[(4-chloroanilino)-oxomethyl]-4,6-diiodophenyl] ester::acetic acid [2-[(4-chlorophenyl)carbamoyl]-4,6-diiodo-phenyl] ester::cid_26695

SMILES: CC(=O)Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=ICKMASVVMCGZLR-UHFFFAOYSA-N

Data: 2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 76289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NLRP3 protein (Homo sapiens (Human))	BDBM76289 (MLS001249435 | SMR000718656 | [2-[(4-chlorophenyl)...) Show SMILES CC(=O)Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H10ClI2NO3/c1-8(20)22-14-12(6-10(17)7-13(14)18)15(21)19-11-4-2-9(16)3-5-11/h2-7H,1H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	813	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RN369N
					More data for this Ligand-Target Pair
NLRP3 protein (Homo sapiens (Human))	BDBM76289 (MLS001249435 | SMR000718656 | [2-[(4-chlorophenyl)...) Show SMILES CC(=O)Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C15H10ClI2NO3/c1-8(20)22-14-12(6-10(17)7-13(14)18)15(21)19-11-4-2-9(16)3-5-11/h2-7H,1H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WD3Z10
					More data for this Ligand-Target Pair