BDBM7989 (3S,4S)-5-(4-Bromobenzyloxy)-4-diphenylacetylamino-3-hydroxypentanoic Acid [(S)-1-((S)-1-Carbamoyl-3-methylbutylcarbamoyl)ethyl]amide::(3S,4S)-5-[(4-bromophenyl)methoxy]-N-[(1S)-1-{[(1S)-1-carbamoyl-3-methylbutyl]carbamoyl}ethyl]-4-(1,1-diphenylacetamido)-3-hydroxypentanamide::Statine-like inhibitor 28

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](COCc1ccc(Br)cc1)NC(=O)C(c1ccccc1)c1ccccc1)C(N)=O

InChI Key InChIKey=ZSGAOIDLHPQPEQ-SUFMYBPMSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7989   

TargetCathepsin D(Homo sapiens (Human))
Linkoping University

LigandPNGBDBM7989((3S,4S)-5-(4-Bromobenzyloxy)-4-diphenylacetylamino...)
Affinity DataKi:  52nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
Linkoping University

LigandPNGBDBM7989((3S,4S)-5-(4-Bromobenzyloxy)-4-diphenylacetylamino...)
Affinity DataKi:  57nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Linkoping University

LigandPNGBDBM7989((3S,4S)-5-(4-Bromobenzyloxy)-4-diphenylacetylamino...)
Affinity DataKi:  139nM ΔG°:  -9.25kcal/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed