BDBM8171 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{2-phenylpyrazolo[1,5-a]pyridazin-3-yl}pyrimidin-2-amine::pyrazolo[1,5-b]pyridazine deriv. 62

SMILES C1COc2cc(Nc3nccc(n3)-c3c(nn4ncccc34)-c3ccccc3)ccc2O1

InChI Key InChIKey=OOFFIMNOURWPHS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8171   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8171(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{2-phenylpy...)
Affinity DataKi:  2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8171(N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-{2-phenylpy...)
Affinity DataIC50: >2.00E+4nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed