BDBM81805 AZAPETINE::CAS_130-83-6::NSC_8966

SMILES C=CCN1Cc2ccccc2-c2ccccc2C1

InChI Key InChIKey=NYGHGTMKALXFIA-UHFFFAOYSA-N

Data  3 KI  2 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 81805   

TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM81805(AZAPETINE | CAS_130-83-6 | NSC_8966)
Show SMILES C=CCN1Cc2ccccc2-c2ccccc2C1
Show InChI InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2C adrenergic receptor(OK)
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM81805(AZAPETINE | CAS_130-83-6 | NSC_8966)
Show SMILES C=CCN1Cc2ccccc2-c2ccccc2C1
Show InChI InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University of Nebraska

Curated by PDSP Ki Database
LigandPNGBDBM81805(AZAPETINE | CAS_130-83-6 | NSC_8966)
Show SMILES C=CCN1Cc2ccccc2-c2ccccc2C1
Show InChI InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
Affinity DataKi:  38nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM81805(AZAPETINE | CAS_130-83-6 | NSC_8966)
Show SMILES C=CCN1Cc2ccccc2-c2ccccc2C1
Show InChI InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
Affinity DataIC50: 205nMAssay Description:Inhibition of specific [3H]-prazosin binding (0.2 nM) to rat brain membranes alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
LigandPNGBDBM81805(AZAPETINE | CAS_130-83-6 | NSC_8966)
Show SMILES C=CCN1Cc2ccccc2-c2ccccc2C1
Show InChI InChI=1S/C17H17N/c1-2-11-18-12-14-7-3-5-9-16(14)17-10-6-4-8-15(17)13-18/h2-10H,1,11-13H2
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of specific [3H]clonidine binding (0.4 nM) to rat brain membranes alpha-2 adrenergic receptorMore data for this Ligand-Target Pair