BDBM82025 1,3-Dipropyl-8-phenylxanthine::8-Phenyl-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CAS_128784::CHEMBL158507::NSC_128784
SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1
InChI Key InChIKey=CLIGSMOZKDCDRZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 82025
Affinity DataKi: 2.80nMAssay Description:Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA).More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Affinity towards adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of binding of 1 nM [3H]N-6-(phenylisopropyl)adenosine to adenosine A1 receptor in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity to A1 adenosine receptor from rat cortical membrane in presence of [3H]-R-(phenylisopropyl)-adenosineMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity for adenosine A1 receptor using [3H]-PIA in rat brain cortical membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
National Institutes Of Health
Curated by ChEMBL
National Institutes Of Health
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via adenosine A2 receptor in human platelet membranes.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity for adenosine A1 receptor from rat brain membranes using [3H]-PIA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity of the compound against A1 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]- PIA binding at adenosine A1 receptor on rat cerebral cortex membranes.More data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes & Digestive & Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes & Digestive & Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 18.9nMAssay Description:Binding affinity at human Adenosine A2B receptor expressed in HEK-293 cells, using [125I]-ABOPX as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes & Digestive & Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes & Digestive & Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 18.9nMAssay Description:Binding affinity for human HEK-293 adenosine A2B receptor using [125I]-ABOPX in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Affinity towards adenosine A2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA).More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Binding affinity for adenosine A2A receptor from rat brain membranes using [3H]-CGS-21,680More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 180nMAssay Description:Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Binding affinity for adenosine A2A receptor using [3H]-NECA in rat brain striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Binding affinity against A2 adenosine receptors of the central nervous systemMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via A2 adenosine receptor in human platelet membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via Adenosine A2 receptor in rat PC12 membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Binding affinity against bovine brain adenosine A1 receptor by using N6-[3H]- cyclohexyladenosineChecked by AuthorMore data for this Ligand-Target Pair