BDBM82519 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1

SMILES [H]C12CCC([H])(CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC)N2C

InChI Key InChIKey=HTMNINCXKXABOI-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 82519   

TargetHistamine H3 receptor(Rattus norvegicus (rat))TBA
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  0.316nMAssay Description:Binding affinity towards rat histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  41.8nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  42nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  48nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  48nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  49nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM82519(4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicycl...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed