BDBM85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853
SMILES Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1
InChI Key InChIKey=OGJGQVFWEPNYSB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 101 hits for monomerid = 85093
Affinity DataKi: 0.400nMAssay Description:Binding affinity against human Dopamine receptor D4 by [3H]-spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D4.2 using [3H]-YM-09151-2 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity towards cloned human Dopamine receptor D4 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity for dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Binding affinity towards human dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [125I]DOI from human dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:In vitro binding affinity to human Dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity evaluated for the displacement of [3H]spiperone against human dopamine receptor D4More data for this Ligand-Target Pair
Affinity DataKi: 0.617nMAssay Description:Ability to displace [3H]spiperone from dopamine receptor D4.4 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:In vitro binding affinity at human dopamine D4 receptor expressed in CHO cells by [3H]spiperone displacement.More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at human SP/Myc epitope-tagged dopamine D4 receptor expressed in HEK293T cells assessed as inhibition of dopamine-induced RLuc8-f...More data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 130nMAssay Description:Binding affinity towards sigma receptor was determinedMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of alpha2B adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Inhibition of alpha2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibition of serotonin 5-HT2 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 226nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of alpha2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Displacement of [3H]N-methylspiperone from human D3R receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
Affinity DataKi: 448nMAssay Description:Binding affinity against human Dopamine receptor D2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 453nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 908nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 908nMAssay Description:Binding affinity at Dopamine receptor D2 in CHO cells by radioligand displacement.More data for this Ligand-Target Pair
Affinity DataKi: 920nMAssay Description:In vitro binding affinity was measured at the cloned human Dopamine receptor D2 using [3H]-spiroperidol as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Binding affinity towards cloned human Dopamine receptor D2 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D2 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.66E+3nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
University Of Nebraska Medical Center
Curated by ChEMBL
University Of Nebraska Medical Center
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of alpha1C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Ability to displace [3H]-spiperone from cloned human dopamine D3 receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Binding affinity towards cloned human Dopamine receptor D3 stably expressed in CHO cells was evaluated using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.31E+3nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair