BDBM85324 CAS_186901-48-4::CORTISTATIN-14::cortistatin14

SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@@H]1CCCN1

InChI Key InChIKey=DDRPLNQJNRBRNY-WYYADCIBSA-N

Data  8 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 85324   

TargetSomatostatin receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  0.450nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  0.450nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  0.570nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  0.910nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  1.77nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  1.94nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  4.46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Novartis Pharma

Curated by PDSP Ki Database
LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataKi:  4.46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataEC50:  140nMpH: 7.4 T: 2°CAssay Description:HTLA cells (HEK-T cells stably expressing a β-arrestin2-TEV fusion protein and a tTa-dependent luciferase reporter) were maintained in DMEM (Cor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMas-related G-protein coupled receptor member X2(Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM85324(CAS_186901-48-4 | CORTISTATIN-14 | cortistatin14)
Affinity DataEC50:  420nMpH: 7.4 T: 2°CAssay Description:MRGPRX2 stable cells were maintained in DMEM containing 10% FBS, 100 μg/ml hygromycin B, and 15 μg/ml blasticidin. For the calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed