BDBM85618 CHEMBL302765::J1.251.181G::MRE 3008F20
SMILES CCCn1cc2c(n1)nc(NC(=O)Nc1ccc(OC)cc1)n1nc(nc21)-c1ccco1
InChI Key InChIKey=CJRNHKSLHHWUAB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 58 hits for monomerid = 85618
Affinity DataKi: 0.290nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]MRE 3008F20 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Binding affinity against human Adenosine A3 receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]MRE-3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 0.63-0.1.00More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-MRE3008-F20 from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]-MRE3008-F20 from human Adenosine A3 receptor expressed in HEK cells; range 0.63-1.0More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of [125I]-AB-MECA binding to human Adenosine A3 receptor expressed in HEK cells; Range 0.63-1.00More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of [3H]-CGS-21,680 binding to human Adenosine A2A receptor expressed in HEK-293 cells; Range 120-155More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-SCH-58,261 from human Adenosine A2A receptor expressed in HEK293 cells; range 120-155More data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-SCH-58,261 from human Adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-SCH 58261 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 120-155More data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Binding affinity against human Adenosine A2A receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 141nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 603nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 120 mins by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 1.13E+3nMAssay Description:Binding affinity to human adenosine A3 receptor measured by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity against human Adenosine A1 receptor in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Tested for inhibitory activity against human adenosine A1 receptor by displacement of [3H]-DPCPX expressed in CHO cells ; value ranges from 1027-1396More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cells; range 1027-1396More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to human Adenosine A1 receptor expressed in CHO cells; Range 1030-1400More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Ferrara
Curated by PDSP Ki Database
University Of Ferrara
Curated by PDSP Ki Database
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
University Of Ferrara
Curated by PDSP Ki Database
University Of Ferrara
Curated by PDSP Ki Database
Affinity DataKi: 1.99E+3nMAssay Description:Displacement of [3H]-SCH- 58261 from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.06E+3nMAssay Description:Inhibition of [3H]-DPCPX binding to human Adenosine A2B receptor expressed in HEK cells; Range 1640-2580More data for this Ligand-Target Pair
Affinity DataKi: 2.06E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A2B receptor expressed in HEK-293 cells; range 1637-2582More data for this Ligand-Target Pair
Affinity DataKi: 2.06E+3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A2B receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.06E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 1637-2582More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP productionMore data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair