BDBM85804 1-Naphthyl(1-butyl-1H-indole-3-yl)methanone::JWH-073::US9416103, JWH-073

SMILES CCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=VCHHHSMPMLNVGS-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 85804   

TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  9.80nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  9.80nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of Arkansas

US Patent
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  12.9nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of Arkansas

US Patent
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  12.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of Arkansas

US Patent
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataKi:  13nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
University Of Arkansas

US Patent
LigandPNGBDBM85804(1-Naphthyl(1-butyl-1H-indole-3-yl)methanone | JWH-...)
Affinity DataEC50:  277nMT: 2°CAssay Description:[35S]GTPγS binding was performed as previously described [Brents et al., PLoS One, 6:e21917]. Briefly, 25 μg of mouse brain homogenates were...More data for this Ligand-Target Pair
In DepthDetails US Patent