BDBM86805 CAS_45263788::NSC_45263788::US9150581, RTI-7527-98::rac-2-(5-(3-chlorophenyl)-6-fluoropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane hydrochloride
SMILES Fc1ncc(cc1-c1cccc(Cl)c1)C1CC2CCC1N2
InChI Key InChIKey=HDPYKJMZSJWSDN-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 86805
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by PDSP Ki Database
Research Triangle Institute
Curated by PDSP Ki Database
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 0.0730nMAssay Description:The Ki values for the inhibition of [3H]epibatidine binding at the α4β2 nAChR in male rat cerebral cortex for compounds are listed in Table...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: >2.00E+3nMAssay Description:Compounds (10 mM) were also evaluated for inhibition of binding to a7 nAChR using [125I]iodoMLA as previously reported in Carroll et al. The binding ...More data for this Ligand-Target Pair