BDBM8971 CHEMBL129108::N-[8-(1,2,3,4-tetrahydroacridin-9-ylsulfanyl)octyl]-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Dimer 4g
SMILES C(CCCCSc1c2CCCCc2nc2ccccc12)CCCNc1c2CCCCc2nc2ccccc12
InChI Key InChIKey=COEYCPFFRLYNSC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 8971
Affinity DataKi: 0.400nMAssay Description:Inhibition of Equine ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of enzyme activity was measured over a substrate concentration range of 0.01-30 mM and at least six inhibitor concentrations to determine ...More data for this Ligand-Target Pair
Affinity DataKi: 1.65nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
Affinity DataKi: 1.65nMAssay Description:Inhibition of human recombinant BuChEMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibition of human butyrylcholine esteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 27.9nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 27.9nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibition of human acetylcholine esteraseMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibition of fetal Bovine serum AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKi: 250nM ΔG°: -9.00kcal/molepH: 8.0 T: 2°CAssay Description:Inhibition of enzyme activity was measured over a substrate concentration range of 0.01-30 mM and at least six inhibitor concentrations to determine ...More data for this Ligand-Target Pair