BDBM9020 3-(1H-Indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-9-yl-amino)pentyl]propionamide::3-(1H-indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-9-ylamino)pentyl]propanamide::Indole-Tacrine Heterodimer 3

SMILES O=C(CCc1c[nH]c2ccccc12)NCCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=YYNNNHICPRTURU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9020   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9020(3-(1H-Indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  70nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9020(3-(1H-Indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9020(3-(1H-Indol-3-yl)-N-[5-(1,2,3,4-tetrahydroacridin-...)
Affinity DataIC50:  1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed