BDBM9038 Indole-Tacrine Heterodimer 21::N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-4-(1H-indol-3-yl)butyramide::N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-4-(1H-indol-3-yl)butanamide

SMILES Clc1ccc2c(NCCCCCCNC(=O)CCCc3c[nH]c4ccccc34)c3CCCCc3nc2c1

InChI Key InChIKey=XXQFKMLSSFZKTL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9038   

TargetAcetylcholinesterase(Bos taurus (bovine))
Neuropharma

LigandPNGBDBM9038(Indole-Tacrine Heterodimer 21 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  0.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9038(Indole-Tacrine Heterodimer 21 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Neuropharma

LigandPNGBDBM9038(Indole-Tacrine Heterodimer 21 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  5.60nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed