BDBM9061 Homodimeric Tacrine Analog 4c::N,N-Bis-(2,3,4,5-tetrahydro-1H-cyclohepta[1,2,-b]quinolin-10-yl)-1,8-diaminooctane::N-(8-{6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-ylamino}octyl)-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-amine

SMILES C(CCCCNc1c2CCCCCc2nc2ccccc12)CCCNc1c2CCCCCc2nc2ccccc12

InChI Key InChIKey=ZCQVAGLFOBYHQJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 9061   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
National Defense Medical Center

LigandPNGBDBM9061(Homodimeric Tacrine Analog 4c | N,N-Bis-(2,3,4,5-t...)
Affinity DataIC50:  1.60nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9061(Homodimeric Tacrine Analog 4c | N,N-Bis-(2,3,4,5-t...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Defense Medical Center

LigandPNGBDBM9061(Homodimeric Tacrine Analog 4c | N,N-Bis-(2,3,4,5-t...)
Affinity DataIC50:  3.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
National Defense Medical Center

LigandPNGBDBM9061(Homodimeric Tacrine Analog 4c | N,N-Bis-(2,3,4,5-t...)
Affinity DataIC50:  333nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed