BDBM92261 CS251

SMILES NC[C@H](NC(=O)c1ccc(cc1)C#Cc1ccccc1)C(=O)NO

InChI Key InChIKey=DAUPXPHTYGUEQU-INIZCTEOSA-N

Data  1 KI  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92261   

LigandPNGBDBM92261(CS251)
Affinity DataKi:  10nM ΔG°:  -10.9kcal/molepH: 7.0 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM92261(CS251)
Affinity DataIC50:  15nMAssay Description:Inhibition of Escherichia coli str. K-12 substr. MG1655 LpxC using UDP-3-O-(R-3-hydroxydecanoyl)-N-acetylglucosamine as substrate preincubated for 20...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
D3R/Abbott

LigandPNGBDBM92261(CS251)
Affinity DataKd:  108nMAssay Description:Thermofluor_Method1More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM92261(CS251)
Affinity DataKd:  108nMpH: 7.0 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM92261(CS251)
Affinity DataKd:  2.67E+3nMpH: 7.0 T: 2°CAssay Description:ITCMore data for this Ligand-Target Pair
In DepthDetails PubMed