BDBM93049 TLM analog, 6

SMILES C\C(C=C)=C/[C@@]1(C)SC(=O)C(C(=O)C(F)(F)F)C1=O

InChI Key InChIKey=LBTAGUWZIVHPJR-LOXSKETOSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 93049   

Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93049(TLM analog, 6)
Affinity DataKi:  460nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93049(TLM analog, 6)
Affinity DataKi:  1.21E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93049(TLM analog, 6)
Affinity DataKd:  2.18E+4nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed