BDBM93415 PHD Inhibitor, 8{5}

SMILES CC(=O)N[C@@H](CO)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1

InChI Key InChIKey=DYHVPZFRGXRRCV-LBPRGKRZSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 93415   

TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen Inc

LigandPNGBDBM93415(PHD Inhibitor, 8{5})
Show SMILES CC(=O)N[C@@H](CO)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1
Show InChI InChI=1S/C19H22N4O8/c1-9(25)22-12(8-24)17(29)20-6-10-3-4-13-11(5-10)16(28)15(19(31)23(13)2)18(30)21-7-14(26)27/h3-5,12,24,28H,6-8H2,1-2H3,(H,20,29)(H,21,30)(H,22,25)(H,26,27)/t12-/m0/s1
Affinity DataIC50: 265nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair