BDBM93423 PHD Inhibitor, 12{2,3,2}::PHD Inhibitor, 12{2,4,2}

SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1

InChI Key InChIKey=MUUFKPHKUZXIMS-CLJLJLNGSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 93423   

TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  37.4nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  90.2nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  13.5nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  12.2nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  11.7nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Amgen

LigandPNGBDBM93423(PHD Inhibitor, 12{2,3,2} | PHD Inhibitor, 12{2,4,2...)
Affinity DataIC50:  7.20nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed