BDBM9933 (2S)-2-(2-{3-[(2S)-2-[(3S,4S)-4-cyclohexyl-3-hydroxy-4-{[(2-methylpropoxy)carbonyl]amino}butanamido]-3-cyclopropylpropanamido]-4-cyclopropyl-2-oxobutanamido}acetamido)-2-phenylacetic acid::depeptidized alpha-ketoamide inhibitor 29
SMILES CC(C)COC(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC1CC1)C(=O)NC(CC1CC1)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1)C1CCCCC1
InChI Key InChIKey=LLRMRSHFSJSNEP-ATAJVBCNSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 9933
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataKi: 4.20E+4nM ΔG°: -6.07kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair