BDBM9934 (2S)-2-{2-[3-({[(2S,3S)-3-cyclohexyl-2-hydroxy-3-{[(2-methylpropoxy)carbonyl]amino}propyl](cyclopropylmethyl)carbamoyl}amino)-4-cyclopropyl-2-oxobutanamido]acetamido}-2-phenylacetic acid::depeptidized alpha-ketoamide inhibitor 30

SMILES CC(C)COC(=O)N[C@H]([C@@H](O)CN(CC1CC1)C(=O)NC(CC1CC1)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1)C1CCCCC1

InChI Key InChIKey=GKFOSUIIDWOOBE-OOWXYQDFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9934   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9934((2S)-2-{2-[3-({[(2S,3S)-3-cyclohexyl-2-hydroxy-3-{...)
Affinity DataKi:  1.00E+4nM ΔG°:  -6.93kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed