BDBM9937 (2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-N-methyl-2-{[(2-methylpropoxy)carbonyl]amino}acetamido]-3-cyclopropylpropanamido]-4-cyclopropyl-2-oxobutanamido}acetamido)-2-phenylacetic acid::depeptidized alpha-ketoamide inhibitor 33

SMILES CC(C)COC(=O)N[C@@H](C1CCCCC1)C(=O)N(C)[C@@H](CC1CC1)C(=O)NC(CC1CC1)C(=O)C(=O)NCC(=O)N[C@H](C(O)=O)c1ccccc1

InChI Key InChIKey=NRBGWZQULLFDCQ-OOWXYQDFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9937   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM9937((2S)-2-(2-{3-[(2S)-2-[(2S)-2-cyclohexyl-N-methyl-2...)
Affinity DataKi:  120nM ΔG°:  -9.59kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed