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Found 275 Enz. Inhib. hit(s) with Target = '1,3-beta-glucan synthase'
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
Leiden University

Curated by ChEMBL
LigandPNGBDBM97255(2-(1-bromanylnaphthalen-2-yl)oxy-N-pyridin-3-yl-et...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity to Kv11.1 channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50:  0.117nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50:  0.171nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100335(CHEMBL2371681 | RO-09-3655 derivative)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100338(CHEMBL267407 | RO-09-3655 derivative)
Affinity DataIC50:  0.25nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100332(CHEMBL415843 | RO-09-3655 derivative)
Affinity DataIC50:  0.280nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100333(CHEMBL2371765 | RO-09-3655 derivative)
Affinity DataIC50:  0.630nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100331(CHEMBL2371715 | RO-09-3655 derivative)
Affinity DataIC50:  0.830nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  0.877nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  0.880nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100329(CHEMBL2371727 | RO-09-3655 derivative)
Affinity DataIC50:  0.890nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100337(CHEMBL2371766 | RO-09-3655 derivative)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289910(1N-[21-(2-aminoethoxy)-3-(3-amino-1-hydroxypropyl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50366679(CHEMBL1793852 | MK-991)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100336(CHEMBL405487 | RO-09-3655 derivative)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289923(1N-[21-(2-aminoethoxy)-3-[3-(1,4-diaminobutylcarbo...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50096797(CHEMBL2370665 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  2nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289914(1N-[21-(2-aminoethoxy)-3-[3-(1,5-diaminopentylcarb...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289922(1N-[3-[3-(1,4-diaminobutylcarboxamido)-1-hydroxypr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100334(CHEMBL407924 | RO-09-3655 derivative)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289924(1N-[21-(2-aminoethoxy)-3-[3-(1,2-diaminoethylcarbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50:  4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50096795(CHEMBL2370654 | Macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50285488(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289917(1N-[21-(2-aminoethoxy)-3-[3-(1,3-diaminopropylcarb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50096793(CHEMBL2370666 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Pichia kudriavzevii)
Rutgers University

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of FKS1 from Candida krusei 98 isolateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50285479(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50285491(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50503151(CHEMBL4450420)
Affinity DataIC50:  7.90nMAssay Description:Negative allosteric modulation of human GluN2A receptor expressed in HEK cells assessed as reduction in 3 uM glycine/glutamate-induced intracellular ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50096799(CHEMBL2369134 | macrocyclic lipopeptidolactone der...)
Affinity DataIC50:  8nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase (GS) from candida albicansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50100339(CHEMBL438198 | FR-901469 | FR901469 | Lipopeptidol...)
Affinity DataIC50:  8.5nMAssay Description:In vitro inhibitory activity against Beta glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans)
Public Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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