Found 37 Enz. Inhib. hit(s) with Target = 'Carbapenem-hydrolyzing beta-lactamase KPC' 
Affinity DataKi: 1.90nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 11nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.55E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.77E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.81E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.84E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.93E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.96E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.36E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.41E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.69E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.89E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.94E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.15E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.23E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5.66E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.04E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.49E+3nMAssay Description:Inhibition of KPC-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella pneumoniae)
Bicetre Hospital
Curated by ChEMBL
Bicetre Hospital
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of carbapenem-resistant Klebsiella pneumoniae carbepenem-hydrolyzing beta-lactamase KPC-1More data for this Ligand-Target Pair
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella pneumoniae)
Bicetre Hospital
Curated by ChEMBL
Bicetre Hospital
Curated by ChEMBL
Affinity DataIC50: 374nMAssay Description:Inhibition of Klebsiella pneumoniae KPC-1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGEMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of Klebsiella pneumoniae KPC-2More data for this Ligand-Target Pair
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella pneumoniae)
Bicetre Hospital
Curated by ChEMBL
Bicetre Hospital
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of carbapenem-resistant Klebsiella pneumoniae carbepenem-hydrolyzing beta-lactamase KPC-1More data for this Ligand-Target Pair
