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Found 417 Enz. Inhib. hit(s) with Target = 'Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3)'
LigandPNGBDBM285598(3-(3-chloro-4-methylphenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285534(3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  2.35nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285634(3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...)
Affinity DataIC50:  4.69nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285537(3-(4-chloro-3-fluoro-phenyl)-N-cyclopropyl-imidazo...)
Affinity DataIC50:  6.84nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577126(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  9.07nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285572(3-(4-chloro-3-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  11.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577123(10-(4-Chloro-5-fluoro-2-methylphenyl)-8-cyclopropy...)
Affinity DataIC50:  12.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285556(3-(4-chloro-3-fluorophenyl)-N-propylimidazo[1,2-b]...)
Affinity DataIC50:  13.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285568(N-cyclopropyl-3-(3-fluoro-4-methylphenyl)imidazo[1...)
Affinity DataIC50:  16.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577135(8-Cyclopropyl-10-(3,4,5-trifluorophenyl)-7,8-dihyd...)
Affinity DataIC50:  17.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285540(US10077269, Example 13 | US10669279, Example 13 | ...)
Affinity DataIC50:  17.3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285576(US10077269, Example 49 | US10669279, Example 49 | ...)
Affinity DataIC50:  19nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577143(10-(3-Chlorophenyl)-8-cyclopropyl-7,8-dihydropyrid...)
Affinity DataIC50:  19.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285627(3-(4-chloro-5-fluoro-2-methylphenyl)-N-(propan-2-y...)
Affinity DataIC50:  20nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285563(3-(3-chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...)
Affinity DataIC50:  21nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577172(10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-3,4,7,8...)
Affinity DataIC50:  21.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285603(US10077269, Example 76 | US10669279, Example 76 | ...)
Affinity DataIC50:  22.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577128(2-Chloro-5-(8-cyclopropyl-9-oxo-6,7,8,9-tetrahydro...)
Affinity DataIC50:  23.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285574(US10077269, Example 47 | US10669279, Example 47 | ...)
Affinity DataIC50:  23.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285557(3-(4-chlorophenyl)-N-(2-methylcyclopropyl)imidazo[...)
Affinity DataIC50:  24.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285602(N-cyclopropyl-3-[2-(difluoro-methoxy)pyridin-4-yl]...)
Affinity DataIC50:  24.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285616(US10077269, Example 86 | US10669279, Example 86 | ...)
Affinity DataIC50:  25nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285595(3-(4-chloro-2-fluorophenyl)-N-[(1R,2S)-2-fluorocyc...)
Affinity DataIC50:  25.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285620(3-(4-cyano-3-fluorophenyl)-N-cyclopropylimidazo[1,...)
Affinity DataIC50:  25.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285611(3-(4-chloro-3-fluorophenyl)-N-ethylimidazo[1,2-b]p...)
Affinity DataIC50:  25.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285529(3-(4-Chlorophenyl)-N-cyclopropylimidazo[1,2-b]pyri...)
Affinity DataIC50:  27.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577130(10-(3-Chloro-4-fluorophenyl)-8-cyclopropyl-7,8-dih...)
Affinity DataIC50:  28.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577094((7S)-10-(4-Chlorophenyl)-8-cyclopropyl-7-methyl-7,...)
Affinity DataIC50:  28.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577182(10-Cyclopentyl-8-cyclopropyl-7,8-dihydropyrido[2',...)
Affinity DataIC50:  29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285626(3-(4-chloro-2,5-difluoro-phenyl)-N-ethylimidazo[1,...)
Affinity DataIC50:  29.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577174(8-Acetyl-10-(4-chlorophenyl)-7,8-dihydropyrido[2',...)
Affinity DataIC50:  30.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285534(3-(4-Chloro-3-fluorophenyl)-N-(1-methyl-1H-pyrazol...)
Affinity DataIC50:  34.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577079(4-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2&...)
Affinity DataIC50:  36.3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM285562(3-(3-chloro-5-fluorophenyl)-N-cyclopropylimidazo[1...)
Affinity DataIC50:  37nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577152(10-(4-Chlorophenyl)-8-(5-methyl-1,2-oxazol-3-yl)-7...)
Affinity DataIC50:  38.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285573(3-(4-chlorophenyl)-N-[(1R,2S)-2-fluorocyclopro-pyl...)
Affinity DataIC50:  39.3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285613(US10077269, Example 83 | US10669279, Example 83 | ...)
Affinity DataIC50:  40nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285536(3-(4-Chloro-2,5-difluorophenyl)-N-cyclopropylimida...)
Affinity DataIC50:  40.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285622(3-(4-cyano-2,5-difluorophenyl)-N-cyclopropylimidaz...)
Affinity DataIC50:  42.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577176(10-(4-Chlorophenyl)-N-ethyl-9-oxo-6,7-dihydropyrid...)
Affinity DataIC50:  42.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285612(3-(4-chloro-3-fluorophenyl)-N-(1H-pyrazol-4-yl)imi...)
Affinity DataIC50:  43.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285614(US10077269, Example 84 | US10669279, Example 84 | ...)
Affinity DataIC50:  44.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577101(4-(8-Cyclopropyl-9-oxo-3,4,6,7,8,9-hexahydro-2H-py...)
Affinity DataIC50:  45.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285550(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  45.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285561(3-(3-chloro-5-fluorophenyl)-N-propylimidazo[1,2-b]...)
Affinity DataIC50:  47nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285615(3-(4-chlorophenyl)-N-ethylimidazo[1,2-b]pyridazine...)
Affinity DataIC50:  47.2nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285555(3-(3,5-dichlorophenyl)-N-propylimidazo[1,2-b]pyrid...)
Affinity DataIC50:  49nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285530(Azetidin-1-yl[3-(3,5-difluoro-4-methoxyphenyl)imid...)
Affinity DataIC50:  51.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM577173(10-(4-Chloro-2,5-difluorophenyl)-8-cyclopropyl-3,4...)
Affinity DataIC50:  56.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM285612(3-(4-chloro-3-fluorophenyl)-N-(1H-pyrazol-4-yl)imi...)
Affinity DataIC50:  56.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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