Compile Data Set for Download or QSAR
maximum 50k data
Found 244 Enz. Inhib. hit(s) with Target = 'NUAK family SNF1-like kinase 1'
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248946(CHEMBL1908392 | US10981896, Compound 16)
Affinity DataKi:  1.70nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged NUAK1 expressed in baculovirus infected Sf9 insect cells using CHK peptide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248946(CHEMBL1908392 | US10981896, Compound 16)
Affinity DataKi:  1.70nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248938(CHEMBL4089284 | US10981896, Compound 21)
Affinity DataKi:  8.60nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged NUAK1 expressed in baculovirus infected Sf9 insect cells using CHK peptide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248938(CHEMBL4089284 | US10981896, Compound 21)
Affinity DataKi:  8.60nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248937(CHEMBL4062168 | US10981896, Compound 15)
Affinity DataKi:  11nMAssay Description:Candidates for inhibitor selectivity characterization were chosen based on an initial single-timepoint commercial kinome profiling screen performed w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50248937(CHEMBL4062168 | US10981896, Compound 15)
Affinity DataKi:  11nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged NUAK1 expressed in baculovirus infected Sf9 insect cells using CHK peptide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50224883(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)
Affinity DataKi: >1.50E+3nMAssay Description:Inhibition of ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human ARK5 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human ARK5 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human ARK5 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human ARK5 using KKKVSRSGLYRSPSMPENLNRPR as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587681(CHEMBL5176650)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587675(CHEMBL4303523)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587675(CHEMBL4303523)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50152595(CHEMBL3780091)
Affinity DataIC50:  2nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587679(CHEMBL5199998)
Affinity DataIC50:  3nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587677(CHEMBL5173501)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50468574(CHEMBL4116008 | US11414410, Example 100)
Affinity DataIC50:  4nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50536679(CHEMBL4568087)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of full-length recombinant human His-tagged NUAK1 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587683(CHEMBL5196626)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM17051(BX-795 | BX-795, 3 | N-(3-{[5-iodo-4-({3-[(thiophe...)
Affinity DataIC50:  5nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50447512(CHEMBL3115681)
Affinity DataIC50:  5nMAssay Description:Inhibition of human NUAK1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50447512(CHEMBL3115681)
Affinity DataIC50:  5nMAssay Description:Inhibition of ARK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50208911(CHEMBL3884319)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant full length His-tagged NUAK1 expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM86615(Benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one, 2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587672(CHEMBL5192992)
Affinity DataIC50:  7nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ARK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50055496(CHEMBL3326006)
Affinity DataIC50:  8nMAssay Description:Inhibition of Nuak1 (unknown origin) by Off-chip Mobility Shift AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50055496(CHEMBL3326006)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal GST-tagged full length human NuaK1 (1 to 661 end residues) expressed in baculovirus expression system using fluorecence-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587682(CHEMBL5204647)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50: <10nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50536675(CHEMBL4569508)
Affinity DataIC50:  15nMAssay Description:Inhibition of full-length recombinant human His-tagged NUAK1 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587673(CHEMBL5175737)
Affinity DataIC50:  15nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587670(CHEMBL5202161)
Affinity DataIC50:  17nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50536678(CHEMBL4550702)
Affinity DataIC50:  19nMAssay Description:Inhibition of full-length recombinant human His-tagged NUAK1 expressed in baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50598717(CHEMBL5193702 | US20230348487, Example LS 6-45)
Affinity DataIC50:  25nMAssay Description:Inhibition of human ARK5More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50383274(CHEMBL1229592 | US10167264, WZ4002 | US9670213, WZ...)
Affinity DataIC50:  25nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50389154(CHEMBL2064666)
Affinity DataIC50:  26nMAssay Description:Inhibition of human ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587669(CHEMBL5190521)
Affinity DataIC50:  30nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587674(CHEMBL1643963)
Affinity DataIC50:  33nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587684(CHEMBL5169640)
Affinity DataIC50:  35nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50:  47nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  48nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50:  64nMAssay Description:Inhibition of NUAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587676(CHEMBL5195181)
Affinity DataIC50:  67nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50587671(CHEMBL4303250)
Affinity DataIC50:  100nMAssay Description:Inhibition of N-terminal GST-tagged wild type human NUAK1 expressed in Escherichia coli DH5alpha incubated for 30 mins in presence of gamma-[32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50469353(CHEMBL4283353)
Affinity DataIC50: >100nMAssay Description:Inhibition of N-terminal GST-tagged full length human NuaK1 (1 to 661 end residues) expressed in baculovirus expression system using fluorecence-labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50553207(CHEMBL4786783)
Affinity DataIC50:  120nMAssay Description:Inhibition of human NAUK1 by kinase-profiling analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50585189(CHEMBL5083125)
Affinity DataIC50:  171nMAssay Description:Inhibition of recombinant human ARK5 (2 to end residues) using KKKVSRSGLYRSPSMPENLNRPR as substrate incubated for 40 mins in presence of [gamma-33ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
The University Of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50585204(CHEMBL5085698)
Affinity DataIC50:  176nMAssay Description:Inhibition of recombinant human ARK5 (2 to end residues) using KKKVSRSGLYRSPSMPENLNRPR as substrate incubated for 40 mins in presence of [gamma-33ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 244 total ) | Next | Last >>
Jump to: