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Found 9 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit beta-4'
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110258((6S)-2-(6-chloropyridin-3-yl)-9-azabicyclo[4.2.1]n...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110262(2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110260(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50023330(1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110259(2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  20nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  73nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Targacept

Curated by PDSP Ki Database
LigandPNGBDBM86311(CAS_485-35-8 | Cytisine | Cytisine-(-) | NSC_22407...)
Affinity DataKi:  176nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rattus norvegicus (Rat))
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110263(2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)
Affinity DataKi:  259nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed